Michelle Monje-Deisseroth

Activity-dependent plasticity of myelin is emerging as a recognized mechanism by which experience can modulate brain structure and function, with roles in motor and cognitive behavioral function. Dysregulation or dysfunction of myelin plasticity can contribute importantly to neurological disease. For example, dysfunction of adaptive myelination can cause impaired cognition following chemotherapy, while subversion of myelin plasticity mechanisms robustly promotes malignant glioma progression.

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