Dr Thomas Knudsen

Developmental Systems Biologist · US EPA National Center for Computational Toxicology and Exposure · company speakers →

Thomas Knudsen is a Developmental Systems Biologist at the US EPA National Center for Computational Toxicology and Exposure, where he is a lead in the Virtual Tissue Models project. His research on prenatal developmental toxicity and systems biology has led to over 150 scientific papers. Current research is focused on building and testing a ‘virtual embryo’ framework for predictive modeling of developmental toxicity. This entails integration of in-vitro data from HTS (high-throughput screening) profiling in ToxCast/Tox21 with biological knowledge of in-vivo embryology and in-silico cell agent-based models for synthetic reconstructing morphogenesis, leading to a quantitative prediction of chemical dysmorphogenesis. Dr. Knudsen is a Past-President of the Teratology Society, Former Editor-in-Chief of Reproductive Toxicology, and currently serves as Editor-in-Chief of Current Research in Toxicology.

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