Catrin Pritchard

Professor of Cancer Biochemistry · Leicester Cancer Research Centre, University of Leicester · company speakers →

Catrin Pritchard is a Professor of Cancer Biochemistry at the University of Leicester with an international reputation in preclinical models for cancer. Her work has involved the use of genetically engineered mouse models for understanding mechanisms underpinning RAS/RAF oncogene-drive tumour development. In the last decade, focus has shifted to the use of a Patient-Derived Explant (PDE) platform, which represents the ex vivo culture of intact fragments of human tumours. The group works with commercial organisations and translational charities to test the efficacy of novel advanced therapies in PDEs and are applying digital pathology solutions at endpoint to identify and validate predictive and pharmacodynamic biomarkers. The approach is being applied to a wide range of human primary and metastatic cancers including breast, colorectal, lung, endometrial, renal cancers as well as melanoma and mesothelioma.

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