Akiko Hayashi-Takagi, MD, PhD

RIKEN Center for Brain Science · company speakers →

Despite the accumulating evidence of synaptopathy in various psychiatric disorders, it is unknown whether synaptopathyis pathogenesis or a secondary consequence. To address this question, we performed a multi-scale synaptic analysis and examined the relationship among synaptic inputs, neuronal computation, and working memory of schizophrenia model mice. Together with the analysis of the postmortem brains of schizophrenia, we offer a new concept for schizophrenia pathomechanism.

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